New Leveraged Biotech ETFs Combine Biologics Revolution with Supercharged Returns

by ETF Base on April 8, 2010

ProShares, the originator of dozens of other leveraged long and short ETFs has now launched a Daily 2X Return ETF for both the long and short Nasdaq Biotechnology Index.  I highlighted earlier in the week how there are several non-leveraged Biotech ETFs with varying returns due to their composition, but many of them are breaking multi-year highs nonetheless given the flurry of activity in the space.  As large pharmas scramble to fill voids left by expiring blockbusters and biotechs simultaneously commercialize viable candidates, now is the nexus of the next leg in the Biotech bull market.  These new leveraged ETFs will allow for supercharged near term trading returns, but as always, I do not suggest holding them long-term due to leveraged ETF decay.

The tickers are as follows:

(BIB) Ultra NasdaqBiotechnology        +200% Daily

(BIS) UltraShort NasdaqBiotechnology   -200% Daily

The NASDAQ Biotechnology Index is calculated under a modified capitalization-weighted methodology. The index is comprised of the following companies:

ACOR        Acorda Therapeutics, Inc.
ADLR        Adolor Corporation
AFFX        Affymetrix, Inc.
AKRX        Akorn, Inc.
AMRI        Albany Molecular Research, Inc.
ALXN        Alexion Pharmaceuticals, Inc.
ALXA        Alexza Pharmaceuticals, Inc.
ALKS        Alkermes, Inc.
ALTH        Allos Therapeutics, Inc.
ALNY        Alnylam Pharmaceuticals, Inc.
AMAG        AMAG Pharmaceuticals, Inc.
AMGN        Amgen Inc.
AMLN        Amylin Pharmaceuticals, Inc.
ARNA        Arena Pharmaceuticals, Inc.
ARIA        ARIAD Pharmaceuticals, Inc.
ARQL        ArQule, Inc.
ARRY        Array BioPharma Inc.
AUXL        Auxilium Pharmaceuticals, Inc.
BCRX        BioCryst Pharmaceuticals, Inc.
BIOD        Biodel Inc.
BIIB        Biogen Idec Inc
BMRN        BioMarin Pharmaceutical Inc.
BMTI        BioMimetic Therapeutics, Inc.
BJGP        BMP Sunstone Corporation
CADX        Cadence Pharmaceuticals, Inc.
CRME        Cardiome Pharma Corporation
CRA        Celera Corporation
CELG        Celgene Corporation
CEPH        Cephalon, Inc.
CSKI        China Sky One Medical, Inc.
CBRX        Columbia Laboratories, Inc.
CRXL        Crucell NV
CBST        Cubist Pharmaceuticals, Inc.
CYPB        Cypress Bioscience, Inc.
CYTK        Cytokinetics, Incorporated
DNDN        Dendreon Corporation
DEPO        Depomed, Inc.
DSCO        Discovery Laboratories, Inc.
DRRX        Durect Corporation
DYAX        Dyax Corp.
ENDP        Endo Pharmaceuticals Holdings Inc.
ENZN        Enzon Pharmaceuticals, Inc.
EXEL        Exelixis, Inc.
FACT        Facet Biotech Corporation
FLML        Flamel Technologies S.A.
GPRO        Gen-Probe Incorporated
GHDX        Genomic Health, Inc.
GENZ        Genzyme Corporation
GERN        Geron Corporation
GILD        Gilead Sciences, Inc.
GTXI        GTx, Inc.
HALO        Halozyme Therapeutics, Inc.
HITK        Hi-Tech Pharmacal Co., Inc.
HGSI        Human Genome Sciences, Inc.
IDIX        Idenix Pharmaceuticals, Inc.
ILMN        Illumina, Inc.
IMGN        ImmunoGen, Inc.
IMMU        Immunomedics, Inc.
IPXL        Impax Laboratories, Inc.
INCY        Incyte Corporation
ISPH        Inspire Pharmaceuticals, Inc.
ITMN        InterMune, Inc.
ISIS        Isis Pharmaceuticals, Inc.
LXRX        Lexicon Pharmaceuticals, Inc.
LIFE        Life Technologies Corporation
LGND        Ligand Pharmaceuticals Incorporated
LMNX        Luminex Corporation
MNKD        MannKind Corporation
MAXY        Maxygen, Inc.
MDVN        Medivation, Inc.
MITI        Micromet, Inc.
MBRK        MiddleBrook Pharmaceuticals, Inc.
MNTA        Momenta Pharmaceuticals, Inc.
MYL        Mylan Inc.
MYGN        Myriad Genetics, Inc.
NABI        Nabi Biopharmaceuticals
NKTR        Nektar Therapeutics
NBIX        Neurocrine Biosciences, Inc.
NVAX        Novavax, Inc.
NPSP        NPS Pharmaceuticals, Inc.
OMPI        Obagi Medical Products, Inc.
ONXX        ONYX Pharmaceuticals, Inc.
OPTR        Optimer Pharmaceuticals, Inc.
OREX        Orexigen Therapeutics, Inc.
OSIP        OSI Pharmaceuticals Inc.
OSIR        Osiris Therapeutics, Inc.
PTIE        Pain Therapeutics
PDLI        PDL BioPharma, Inc.
PRGO        Perrigo Company
VRUS        Pharmasset, Inc.
PARD        Poniard Pharmaceuticals, Inc.
POZN        Pozen, Inc.
PGNX        Progenics Pharmaceuticals Inc.
QGEN        Qiagen N.V.
QLTI        QLT Inc.
QCOR        Questcor Pharmaceuticals, Inc.
REGN        Regeneron Pharmaceuticals, Inc.
RIGL        Rigel Pharmaceuticals, Inc.
SLXP        Salix Pharmaceuticals, Ltd.
SGMO        Sangamo BioSciences, Inc.
SNTS        Santarus, Inc.
SVNT        Savient Pharmaceuticals Inc
SGEN        Seattle Genetics, Inc.
SQNM        Sequenom, Inc.
SHPGY        Shire plc
SIGA        SIGA Technologies Inc.
SPPI        Spectrum Pharmaceuticals, Inc.
STEM        StemCells, Inc.
SUPG        SuperGen, Inc.
SNTA        Synta Pharmaceuticals Corp.
TRGT        Targacept, Inc.
TECH        Techne Corporation
TEVA        Teva Pharmaceutical Industries Limited
MDCO        The Medicines Company
THRX        Theravance, Inc.
UTHR        United Therapeutics Corporation
VNDA        Vanda Pharmaceuticals Inc.
VRTX        Vertex Pharmaceuticals Incorporated
VICL        Vical Incorporated
VPHM        ViroPharma Incorporated
VVUS        VIVUS, Inc.
WCRX        Warner Chilcott plc
XNPT        XenoPort, Inc.
XOMA        XOMA Ltd.
ZGEN        ZymoGenetics, Inc.

Disclosure: no position in either BIB, BIS or any other Biotech ETFs.

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